Early treatment of Menopause with estrogen patch can preserve brain function and reduce the risk of Alzheimer’s disease, according to a Mayo Clinic study published in the Journal of Alzheimer’s Disease.
According to the study newly postmenopausal women who received transdermal 17β-Estradiol via a skin patch had reduced beta-amyloid deposits. These plaque deposits are found in the brains of individuals with Alzheimers and harm cognitive function.The study indicates that decrease in Amyloid deposition was not associated with women treated with oral estrogen.
Women with the APOE e4 genotype who are genetically predisposed to developing Alzheimer’s particularly benefited from this therapy.
Read Full Research Article: http://content.iospress.com/articles/journal-of-alzheimers-disease/jad160258
Kantarci, Kejal, et al. “Early Postmenopausal Transdermal 17β-Estradiol Therapy and Amyloid-β Deposition.” Journal of Alzheimer’s Disease Preprint (2016): 1-10.